589 research outputs found
Computation of three-dimensional electromagnetic field in the eddy-current testing of steel pipes
The computation of three-dimensional electromagnetic field distributions in the eddy-current testing for holes in steel pipes is described. A boundary element method with vector variables was used to compute the eddy-current and magnetic-flux-density distributions. Computed and experimental results for the magnetic flux density on the inner surface are compared, and the mechanism of defect detection in steel pipes is clarified </p
Predominant Dissemination of PVL-Negative CC89 MRSA with SCCmec Type II in Children with Impetigo in Japan
Background. The ratio of CA-MRSA in children with impetigo has been increasing in Japan. Methods. Antimicrobial susceptibilities of 136 S. aureus isolates from children with impetigo were studied. Furthermore, molecular epidemiological analysis and virulence gene analysis were performed. Results. Of the 136 S. aureus isolates, 122 (89.7%) were MSSA and 14 (10.3%) were MRSA. Of the 14 MRSA strains, 11 belonged to CC89 (ST89, ST91, and ST2117) and carried diverse types of SCCmec: type II (IIb: 3 strains; unknown subtype: 4 strains), type IVa (2 strains), and unknown type (2 strains). The remaining three strains exhibited CC8 (ST-8)-SCCmec type VIa, CC121 (ST121)-SCCmec type V, and CC5 (ST5)-nontypeable SCCmec element, respectively. None were lukS-PV-lukF-PV gene positive. Gentamicin- and clarithromycin-resistant strains were frequently found in both MRSA and MSSA. Conclusions. PVL-negative CC89-SCCmec type II strains are the most predominant strains among the CA-MRSA strains circulating in the community in Japan
Limited Lifespan of Fragile Regions in Mammalian Evolution
An important question in genome evolution is whether there exist fragile
regions (rearrangement hotspots) where chromosomal rearrangements are happening
over and over again. Although nearly all recent studies supported the existence
of fragile regions in mammalian genomes, the most comprehensive phylogenomic
study of mammals (Ma et al. (2006) Genome Research 16, 1557-1565) raised some
doubts about their existence. We demonstrate that fragile regions are subject
to a "birth and death" process, implying that fragility has limited
evolutionary lifespan. This finding implies that fragile regions migrate to
different locations in different mammals, explaining why there exist only a few
chromosomal breakpoints shared between different lineages. The birth and death
of fragile regions phenomenon reinforces the hypothesis that rearrangements are
promoted by matching segmental duplications and suggests putative locations of
the currently active fragile regions in the human genome
Severe Chronic Active EBV Infection in an Adult Patient: Case Report
Severe chronic active Epstein-Barr virus (EBV) infection is a rare and life-threatening illness. Although the criteria for diagnosis include chronic or recurrent infectious mononucleosis-like symptoms lasting more than 6 months and high titers of anti-EBV antibodies, clinical and laboratory findings may be heterogeneous and flexible application of those criteria is necessary in cases showing typical clinical and pathologic findings. We report a case of severe chronic active EBV infection in a 62-yr-old female patient who showed classical clinical findings with infiltration of EBV-infected T lymphocytes in the bone marrow, spleen, and lymph nodes, and died four months after presentation
Six-reflection meV-monochromator for synchrotron radiation
A design is presented for a cryogenically stabilized monochromator for 10–40 keV synchrotron radiation that uses six crystal reflections to achieve a meV-bandpass with high efficiency
Synchrotron Radiation Time Gate Quartz Device For Nuclear Resonant Scattering
A synchrotron radiation time gate with X-cut quartz resonator has been constructed for use on nuclear resonant scattering at ultrahigh brilliance beam lines. The purpose is to discriminate the electronic scattered prompt (zero time) from the time delayed nuclear scattered photons. The special feature of this device is the possibility of adjusting the time modulation width of the gate without changing the frequency. © 1995 American Institute of Physics.6622235223
Subaru high-z exploration of low-luminosity quasars (SHELLQs). I. Discovery of 15 quasars and bright galaxies at 5.7 < z < 6.9
We report the discovery of 15 quasars and bright galaxies at 5.7 < z < 6.9.
This is the initial result from the Subaru High-z Exploration of Low-Luminosity
Quasars (SHELLQs) project, which exploits the exquisite multiband imaging data
produced by the Subaru Hyper Suprime-Cam (HSC) Strategic Program survey. The
candidate selection is performed by combining several photometric approaches
including a Bayesian probabilistic algorithm to reject stars and dwarfs. The
spectroscopic identification was carried out with the Gran Telescopio Canarias
and the Subaru Telescope for the first 80 deg2 of the survey footprint. The
success rate of our photometric selection is quite high, approaching 100 % at
the brighter magnitudes (zAB < 23.5 mag). Our selection also recovered all the
known high-z quasars on the HSC images. Among the 15 discovered objects, six
are likely quasars, while the other six with interstellar absorption lines and
in some cases narrow emission lines are likely bright Lyman-break galaxies. The
remaining three objects have weak continua and very strong and narrow Ly alpha
lines, which may be excited by ultraviolet light from both young stars and
quasars. These results indicate that we are starting to see the steep rise of
the luminosity function of z > 6 galaxies, compared with that of quasars, at
magnitudes fainter than M1450 ~ -22 mag or zAB ~24 mag. Follow-up studies of
the discovered objects as well as further survey observations are ongoing.Comment: Published in ApJ (828:26, 2016
Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report
<p>Abstract</p> <p>Introduction</p> <p>Hemophagocytic lymphohistiocytosis is an immune-mediated syndrome that typically has a rapidly progressive course that can result in pancytopenia, coagulopathy, multi-system organ failure and death.</p> <p>Case presentation</p> <p>A 57-year-old Caucasian woman was referred in fulminant hemophagocytic lymphohistiocytosis, with fever, pancytopenia, splenomegaly, mental status changes and respiratory failure. She was found to have stage IV classical Hodgkin lymphoma, in addition to Epstein-Barr virus and cytomegalovirus viremia. Her presentation was preceded by a 3-year prodrome consisting of cytopenia and fever that were partially controlled by steroids and azathioprine.</p> <p>Conclusion</p> <p>Fulminant hemophagocytic lymphohistiocytosis may follow a prodromal phase that possesses features suggestive of a chronic form of hemophagocytic lymphohistiocytosis, but which may also resemble immune cytopenias of other causes. A diagnosis of hemophagocytic lymphohistiocytosis should be considered in the setting of chronic pancytopenia.</p
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